You can if you have the proper tools and know-how. Changing a clutch is a big job on a rear-wheel drive car or truck, and an even tougher job on a front-wheel drive car or minivan.
On a rear-wheel drive vehicle, the driveshaft, transmission and bellhousing have to be removed from underneath the vehicle to get at the clutch. The clutch can then be unbolted from the flywheel and replaced. Resurfacing the flywheel is recommended -- and required if the flywheel is warped, grooved, badly worn, heat discolored and/or contaminated with grease or oil. That means the flywheel has to come out, too. If the flywheel is cracked, it should be replaced.
In addition to replacing the clutch, a new throw-out bearing is also recommended. Considering the labor involved to tear everything apart, it's risky to reuse an old throw-out bearing. It may not be noisy now, but it's hard to tell how many miles it might have left in it.
The pilot bushing in the end of the crankshaft that supports the transmission input shaft should also be inspected. Replacement is recommended if your vehicle has a lot of miles on it.
Reinstalling the transmission is the most difficult part of the job because the transmission is heavy (which means you'll need a floor or transmission jack, or a pair of strong arms). The clutch must also be perfectly aligned (with a pilot tool) so the transmission input shaft will slip into place, once everything has been bolted together.
With front-wheel drive, replacing the clutch is even more difficult because it involves pulling the engine or dropping the transaxle (both of which are major undertakings because of all the disassembly that's involved). For this, you'll need an engine hoist to pull the engine or a hoist or beam to support the engine from above while the transaxle comes out.