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The 2001 Frontier 4X2 Regular Cab is a 2-door, 3-passenger compact pickup, available in one trim only, the XE Regular Cab. The 2001 Frontier 4X2 Regular Cab's closest competitors include the Ford Ranger Regular Cab 2.3L 4x2, the Ford Ranger Regular Cab 2.5L (Discontinued), and the Toyota Tacoma 4X2.
Upon introduction, the Frontier 4X2 Regular Cab is equipped with a standard 2.4-liter, I4, 143-horsepower engine that achieves 22-mpg in the city and 26-mpg on the highway. A 5-speed manual transmission with overdrive is standard, and a 4-speed automatic transmission with overdrive is optional.